Spicy Cajun Chicken Alfredo

Featured in: Everyday Comfort Dishes

This dish features tender chicken breasts coated in vibrant Cajun seasoning and pan-seared to a golden finish. Cooked fettuccine is enveloped in a smooth, creamy Alfredo sauce infused with garlic, smoked paprika, and optional chili flakes for extra kick. The pasta and chicken come together with Parmesan cheese and fresh parsley garnish, creating a luscious, well-balanced meal perfect for spice enthusiasts and lovers of creamy textures. Simple to prepare, it offers rich flavors and comforting textures suited for a medium-level cooking experience.

Updated on Sat, 15 Nov 2025 09:30:00 GMT
Golden-brown Spicy Cajun Chicken Alfredo, creamy pasta with tender chicken, ready to enjoy. Pin Recipe
Golden-brown Spicy Cajun Chicken Alfredo, creamy pasta with tender chicken, ready to enjoy. | fordishes.com

A bold, creamy pasta dish featuring tender Cajun-spiced chicken tossed with fettuccine in a rich Alfredo sauce, perfect for spice lovers.

I first made this Cajun Chicken Alfredo for my friends after a long week, wanting something comforting yet bold. Everyone loved how the Cajun spices brightened up classic Alfredo, and we lingered around the table enjoying second helpings!

Ingredients

  • Chicken: 2 large boneless, skinless chicken breasts; 2 tablespoons Cajun seasoning; 1 tablespoon olive oil
  • Pasta: 340 g (12 oz) fettuccine
  • Alfredo Sauce: 2 tablespoons unsalted butter; 3 cloves garlic (minced); 1 cup (240 ml) heavy cream; 1 cup (100 g) freshly grated Parmesan cheese; 1/2 teaspoon smoked paprika; 1/2 teaspoon chili flakes (optional for extra heat); salt and black pepper (to taste)
  • Garnishes: 2 tablespoons chopped fresh parsley; extra grated Parmesan cheese

Instructions

Cook the Pasta:
Cook fettuccine in salted boiling water until al dente. Reserve 1/2 cup pasta water, drain, and set aside.
Season and Cook Chicken:
Pat chicken breasts dry. Coat evenly with Cajun seasoning. Heat olive oil in skillet over medium-high. Cook chicken 5-6 minutes per side until golden and fully cooked. Remove and let rest 5 minutes, then slice thinly.
Make Alfredo Sauce:
In same skillet over medium, add butter. Sauté minced garlic 1 minute. Stir in heavy cream, smoked paprika, chili flakes. Simmer briefly, whisk in Parmesan until melted and smooth. Season with salt and pepper.
Combine Pasta and Sauce:
Add cooked fettuccine to sauce and toss to coat. Add reserved pasta water as needed for silkier sauce.
Serve:
Top pasta with sliced Cajun chicken. Garnish with chopped parsley and extra Parmesan. Serve immediately.
Pin Recipe
| fordishes.com

When my family requests this recipe, everyone pitches in to grate Parmesan or sprinkle the final parsley. It has become our signature 'celebration pasta' for birthdays and cozy gatherings.

Required Tools

Large pot for boiling pasta, skillet for chicken and sauce, tongs for tossing, chefs knife, cutting board, measuring cups and spoons for precision.

Allergen Information

This Alfredo includes dairy from cream, butter and Parmesan, as well as gluten in the pasta. Always check Cajun seasoning labels for added allergens.

Nutritional Information

Each serving contains 610 calories, 27 g total fat, 54 g carbohydrates, and 38 g protein, making it a hearty main dish.

Delectable Spicy Cajun Chicken Alfredo with vibrant parsley garnish, a comforting weeknight meal. Pin Recipe
Delectable Spicy Cajun Chicken Alfredo with vibrant parsley garnish, a comforting weeknight meal. | fordishes.com

Spicy Cajun Chicken Alfredo is best served piping hot so the sauce stays creamy. Garnish generously with fresh parsley and more Parmesan for maximum satisfaction.

Recipe FAQs

How do I make the Cajun chicken spicy?

Increase the amount of Cajun seasoning or add chili flakes to intensify the heat in the chicken and sauce.

Can I use a different pasta type?

Penne, linguine, or other long pasta can replace fettuccine while keeping a similar texture and sauce coverage.

What is the best way to cook the chicken evenly?

Pat dry and coat the chicken well with seasoning, then cook over medium-high heat 5-6 minutes per side until golden and fully cooked.

How can I make the sauce silkier?

Add reserved pasta water gradually while tossing the pasta to achieve a smooth, creamy consistency.

Are there any good pairing suggestions?

This dish pairs well with crisp white wines such as Sauvignon Blanc and simple green salads to balance richness.

Spicy Cajun Chicken Alfredo

Bold Cajun-spiced chicken and fettuccine blend in a luscious Alfredo sauce delivering creamy, spicy flavor.

Prep Duration
15 mins
Cooking Duration
25 mins
Complete Time
40 mins
Recipe by Fordishes Ava Reynolds


Skill Level Medium

Cuisine American (Cajun-inspired, Italian-American)

Makes 4 Number of Servings

Diet Details None specified

Ingredient List

Chicken

01 2 large boneless, skinless chicken breasts
02 2 tablespoons Cajun seasoning
03 1 tablespoon olive oil

Pasta

01 12 ounces fettuccine

Alfredo Sauce

01 2 tablespoons unsalted butter
02 3 cloves garlic, minced
03 1 cup heavy cream
04 1 cup freshly grated Parmesan cheese
05 1/2 teaspoon smoked paprika
06 1/2 teaspoon chili flakes (optional)
07 Salt and black pepper to taste

Garnishes

01 2 tablespoons chopped fresh parsley
02 Extra grated Parmesan cheese

Directions

Step 01

Cook pasta: Boil salted water and cook fettuccine until al dente per package directions. Reserve 1/2 cup pasta water, drain, and set aside.

Step 02

Prepare chicken: Pat chicken breasts dry and evenly coat them with Cajun seasoning.

Step 03

Cook chicken: Heat olive oil in a large skillet over medium-high heat. Cook chicken 5 to 6 minutes per side until cooked through and golden. Remove, let rest 5 minutes, then slice thinly.

Step 04

Sauté garlic: Reduce skillet heat to medium; add butter and sauté minced garlic for 1 minute until fragrant.

Step 05

Prepare sauce: Stir in heavy cream, smoked paprika, and chili flakes. Simmer gently, then whisk in Parmesan until smooth. Season with salt and pepper.

Step 06

Combine pasta and sauce: Toss cooked fettuccine in Alfredo sauce, adding reserved pasta water gradually to achieve desired consistency.

Step 07

Serve: Top pasta with sliced Cajun chicken, garnish with chopped parsley and extra Parmesan. Serve immediately.

Needed Equipment

  • Large pot
  • Large skillet
  • Tongs
  • Chef's knife
  • Cutting board
  • Measuring cups and spoons

Allergy Info

Double-check ingredients for allergens and speak with a healthcare provider if you're unsure.
  • Contains dairy (butter, cream, Parmesan cheese)
  • Contains gluten (fettuccine)
  • May contain allergens in Cajun seasoning (such as mustard or celery)

Nutrition Information (per serving)

For informational use only—doesn't replace personalized medical direction.
  • Calories: 610
  • Fats: 27 g
  • Carbohydrates: 54 g
  • Proteins: 38 g